Mitochondrial-Derived Metabolic Peptide
MOTS-c is a highly unique peptide encoded by the mitochondrial genome, distinguishing it from nuclear-derived peptides. It specifically targets skeletal muscle, directly mediating metabolic homeostasis, insulin sensitivity, and shifting the metabolic focus towards fatty acid utilization. It is a prime candidate in cellular longevity studies.
Research Applications
- Mitochondrial genomics and metabolic regulation
- AMPK pathway activation and fatty acid oxidation
- Diet-induced insulin resistance models
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